Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Hydroxy-PEG4-CH2COOH

  • CAS No. 70678-95-4

  • Cat. No. CS-0114560
  • Purity≥95%
  • MDL No.MFCD30730373

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG4-CH2COOH|CS-0114560

Structure of 70678-95-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 70678-95-4
  • Cat. No. CS-0114560
  • Purity ≥95%
  • MDL No. MFCD30730373
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀O₇
  • Molecular Weight 252.26
  • Synonym(s) None
  • SMILES O=C(O)COCCOCCOCCOCCO

Description

Hydroxy-PEG4-CH2COOH is a hydrophilic, bifunctional linker featuring a terminal carboxylic acid and a hydroxyl group separated by a four-ethylene glycol unit. This structure enables efficient conjugation to biomolecules or surfaces while maintaining solubility in aqueous environments. The PEG spacer provides steric shielding and reduces non-specific binding.

Application

Hydroxy-PEG4-CH2COOH serves as a versatile bifunctional linker for conjugation and polymer synthesis. The terminal hydroxyl group enables derivatization via esterification or etherification, while the carboxylic acid facilitates amide coupling under standard conditions. Its PEG4 spacer provides enhanced solubility and reduced aggregation, improving performance in bioconjugation and drug delivery applications.

Synthesis

  • Route1
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • null|null
      3926-62-3
    • ~%
    • In-stock
      Hydroxy-PEG4-CH2COOH|CS-0114560
      70678-95-4

    References

    • Chen, Bin; Baumeister, Ute; Pelzl, Gerhard; Das, Malay Kumar; Zeng, Xiangbing; Ungar, Goran; Tschierske, Garsten Journal of the American Chemical Society, 2005 , vol. 127, # 47 p. 16578 - 16591
  • Route2

    References

    • Nakatsuji, Yohji; Kawamura, Norio; Okahara, Mitsuo; Matsushima, Kenji Synthesis, 1981 , # 1 p. 42 - 44
  • Route3
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • null|null
      79-11-8
    • ~58%
    • In-stock
      Hydroxy-PEG4-CH2COOH|CS-0114560
      70678-95-4

    References

    • Yamaguchi, Kazuo; Kuboniwa, Hitoshi; Murakami, Nobuya; Hirao, Akira; Nakahama, Swiichi; Yamazaki, Noburo Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 4 p. 1097 - 1101

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   94.45
  • LogP   -0.8703
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   13

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Hydroxy-PEG4-CH2COOH sigmaHydroxy-PEG4-CH2COOH manufacturerHydroxy-PEG4-CH2COOH priceHydroxy-PEG4-CH2COOH structureHydroxy-PEG4-CH2COOH SDSbuy Hydroxy-PEG4-CH2COOHHydroxy-PEG4-CH2COOH supplierHydroxy-PEG4-CH2COOH usesHydroxy-PEG4-CH2COOH molecular weightprice of Hydroxy-PEG4-CH2COOHHydroxy-PEG4-CH2COOH chemical name formula of Hydroxy-PEG4-CH2COOH
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label