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CS-W001157 4
Total: USD 88.00

Hydroxy-PEG3-CH2-Boc

  • CAS No. 518044-31-0

  • Cat. No. CS-0115007
  • Purity≥97%
  • MDL No.MFCD27977510

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG3-CH2-Boc|CS-0115007

Structure of 518044-31-0

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General Information

  • CAS No. 518044-31-0
  • Cat. No. CS-0115007
  • Purity ≥97%
  • MDL No. MFCD27977510
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄O₆
  • Molecular Weight 264.32
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)COCCOCCOCCO

Description

Hydroxy-PEG3-CH2-Boc features a hydroxyl-terminated PEG3 spacer flanked by a benzyl carbamate (Boc) protecting group. This bifunctional intermediate enables controlled conjugation in peptide synthesis and bioconjugation workflows, offering enhanced solubility and stability under standard conditions.

Application

Hydroxy-PEG3-CH2-Boc serves as a versatile bifunctional linker for peptide and oligonucleotide conjugation, combining the solubility of PEG3 with the orthogonal protection offered by the Boc group. The terminal hydroxyl enables efficient coupling to carboxylic acid-containing substrates, while the Boc moiety can be selectively removed under mild acidic conditions. This reagent exhibits excellent bench stability, facilitates straightforward purification, and supports high-yielding transformations in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   74.22
  • LogP   0.3702
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   10

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