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Hydroxy-PEG2-CH2-Boc

  • CAS No. 149299-82-1

  • Cat. No. CS-0109371
  • Purity≥97%
  • MDL No.MFCD25959245

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG2-CH2-Boc|CS-0109371

Structure of 149299-82-1

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General Information

  • CAS No. 149299-82-1
  • Cat. No. CS-0109371
  • Purity ≥97%
  • MDL No. MFCD25959245
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀O₅
  • Molecular Weight 220.26
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)COCCOCCO

Description

Hydroxy-PEG2-CH2-Boc features a hydroxyl-terminated PEG2 spacer flanked by a benzyl carbamate (Boc) protecting group, enabling selective conjugation and orthogonal deprotection. This bifunctional scaffold integrates seamlessly into peptide and biomolecule synthesis workflows, offering enhanced solubility and controlled reactivity under standard conditions.

Application

Hydroxy-PEG2-CH2-Boc serves as a versatile, bench-stable building block for the synthesis of PEGylated compounds and bioconjugates. The hydroxyl group enables straightforward derivatization, while the Boc-protected amine offers orthogonal functionality for sequential coupling. Its PEG2 spacer provides enhanced solubility and reduced aggregation in aqueous environments, facilitating purification and downstream applications in medicinal chemistry and peptide modification workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.99
  • LogP   0.3536
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   7

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