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CS-W001157 4
Total: USD 88.00

Pentafluorophenol

  • CAS No. 771-61-9

  • Cat. No. CS-W008591
  • Purity≥97%
  • MDL No.MFCD00002156

*For research and further manufacturing use only, not for direct human use.

Pentafluorophenol|CS-W008591

Structure of 771-61-9

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General Information

  • CAS No. 771-61-9
  • Cat. No. CS-W008591
  • Purity ≥97%
  • MDL No. MFCD00002156
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆HF₅O
  • Molecular Weight 184.06
  • Synonym(s) None
  • SMILES OC1=C(F)C(F)=C(F)C(F)=C1F

Description

Pentafluorophenol is widely used as a precursor in both solution and solid-phase peptide synthesis. It is also involved in the preparation of aromatic fluoro derivatives.Pentafluorophenol can be used as a reactant to synthesize pentafluorophenyl esters from:N-protected amino acid in the presence of dicyclohexylcarbodiimide and ethyl acetate.t-Butoxycarbonyl-L-alanylglycinein the presence of 1-ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride.Aliphatic dicarboxylic acids in the presence of pyridine, diisopropylcarbodiimide, and acetonitrile.It can also be used as a reactant to synthesize pentafluorophenyl formate which can be used as a formylating agent in organic synthesis.

Synthesis

  • Route1

    References

    • INTERNATIONAL BUSINESS MACHINES CORPORATION; CENTRAL GLASS CO., LTD. Patent: US2010/305281 A1, 2010 ; Location in patent: Page/Page column 40; 41 ;
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      945841-51-0
    • In-stock
      Pentafluorophenol|CS-W008591
      771-61-9

    References

    • INTERNATIONAL BUSINESS MACHINES CORPORATION; CENTRAL GLASS CO., LTD. Patent: US2010/305281 A1, 2010 ; Location in patent: Page/Page column 11 ;
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    • In-stock
      Pentafluorophenol|CS-W008591
      771-61-9
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      1252553-78-8

    References

    • INTERNATIONAL BUSINESS MACHINES CORPORATION; CENTRAL GLASS CO., LTD. Patent: US2010/305281 A1, 2010 ; Location in patent: Page/Page column 14 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.0877
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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