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Structure of 499-76-3
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4-Hydroxy-3-methylbenzoic acid features a phenolic hydroxyl group ortho to a carboxylic acid, enabling versatile derivatization in synthetic and medicinal chemistry. The methyl substituent enhances electron density at the aromatic ring, supporting stable coupling reactions under standard conditions. This bench-stable, moisture-tolerant reagent integrates readily into complex molecular architectures.
4-Hydroxy-3-methylbenzoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted aromatic scaffolds. Its ortho-hydroxyl and meta-methyl groups provide defined regiochemistry for derivatization, while the carboxylic acid functionality facilitates amide coupling, esterification, and metal complexation. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in multi-step syntheses and process development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: