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Structure of 860296-12-4
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3-Fluoro-5-hydroxybenzoic acid features a strategically positioned fluorine atom and hydroxyl group on the aromatic ring, enabling enhanced electronic modulation and hydrogen bonding capacity. This combination supports efficient conjugation in bioactive molecule synthesis and facilitates solubility in polar reaction media.
3-Fluoro-5-hydroxybenzoic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates, offering orthogonal functionality for selective derivatization. The ortho-fluorine enables electrophilic substitution or palladium-catalyzed coupling, while the phenolic hydroxyl and carboxylic acid groups provide handles for esterification, amidation, or direct conjugation. Bench-stable and readily purified by recrystallization, it functions efficiently in standard synthetic workflows requiring precise regiocontrol and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: