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CS-W001157 4
Total: USD 88.00

4-Fluorobenzimidamide hydrochloride

  • CAS No. 456-14-4

  • Cat. No. CS-W017476
  • Purity≥98%
  • MDL No.MFCD04114421

*For research and further manufacturing use only, not for direct human use.

4-Fluorobenzimidamide hydrochloride|CS-W017476

Structure of 456-14-4

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General Information

  • CAS No. 456-14-4
  • Cat. No. CS-W017476
  • Purity ≥98%
  • MDL No. MFCD04114421
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClFN₂
  • Molecular Weight 174.60
  • Synonym(s) 4-Fluorobenzamidine (hydrochloride)
  • SMILES FC1=CC=C(C(N)=N)C=C1.Cl

Description

4-Fluorobenzimidamide hydrochloride offers a stable, moisture-tolerant platform for medicinal chemistry applications. The fluorinated aromatic ring enhances metabolic resistance, while the imidamide functionality provides a versatile handle for derivatization. This salt form ensures high solubility and ease of handling in aqueous reaction media.

Synthesis

  • Route1
    • Ethyl 4-fluorobenzimidate hydrochloride|CS-0033817
      4278-01-7
    • ~87%
    • In-stock
      4-Fluorobenzimidamide hydrochloride|CS-W017476
      456-14-4

    References

    • Sudheendran, Kavitha; Schmidt, Dietmar; Frey, Wolfgang; Conrad, Juergen; Beifuss, Uwe Tetrahedron, 2014 , vol. 70, # 8 p. 1635 - 1645
  • Route2
    • null|null
      1194-02-1
    • ~49%
    • In-stock
      4-Fluorobenzimidamide hydrochloride|CS-W017476
      456-14-4

    References

    • Terpinski, Jacek; Denney, Dorothy Z.; Beveridge, Richard; Cox, Phillip D.; Moss, Robert A. Magnetic Resonance in Chemistry, 1987 , vol. 25, p. 923 - 927
  • Route3

    References

    • Mahajan, Umesh S.; Godinde, Rupesh R.; Mandhare Synthetic Communications, 2011 , vol. 41, # 15 p. 2195 - 2199

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H301
Precautionary Statements : P264-P270-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.87
  • LogP   1.53157
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

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