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CS-W001157 4
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2,3-Dimethoxybenzylamine

  • CAS No. 4393-09-3

  • Cat. No. CS-0033736
  • Purity≥96%
  • MDL No.MFCD00052392

*For research and further manufacturing use only, not for direct human use.

2,3-Dimethoxybenzylamine|CS-0033736

Structure of 4393-09-3

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General Information

  • CAS No. 4393-09-3
  • Cat. No. CS-0033736
  • Purity ≥96%
  • MDL No. MFCD00052392
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₂
  • Molecular Weight 167.21
  • Synonym(s) [(2,3-Dimethoxyphenyl)methyl]amine; 1-(2,3-dimethoxyphenyl)methanamine
  • SMILES NCC1=CC=CC(OC)=C1OC

Description

2,3-Dimethoxybenzylamine features a benzylamine core adorned with methoxy groups at the 2- and 3-positions, enhancing solubility and electronic donation. This electron-rich scaffold enables efficient coupling in peptide synthesis and serves as a key building block for bioactive molecules. The compound exhibits bench-stable handling under standard conditions and integrates readily into diverse synthetic workflows.

Application

2,3-Dimethoxybenzylamine serves as a versatile building block in medicinal chemistry and natural product synthesis, offering enhanced solubility and metabolic stability compared to unsubstituted analogs. The ortho-dimethoxy substitution pattern stabilizes the benzyl amine moiety against oxidation while enabling facile derivatization via reductive amination or coupling reactions. Its bench-stable, crystalline form facilitates handling and purification, making it ideal for constructing bioactive scaffolds and peptide conjugates in high-throughput screening campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.1625
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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