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CS-W001157 4
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Fmoc-NH-PEG6-CH2COOH

  • CAS No. 437655-96-4

  • Cat. No. CS-0107517
  • Purity≥98%
  • MDL No.MFCD26142983

*For research and further manufacturing use only, not for direct human use.

Fmoc-NH-PEG6-CH2COOH|CS-0107517

Structure of 437655-96-4

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General Information

  • CAS No. 437655-96-4
  • Cat. No. CS-0107517
  • Purity ≥98%
  • MDL No. MFCD26142983
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₃₉NO₁₀
  • Molecular Weight 561.62
  • Synonym(s) None
  • SMILES O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCC(O)=O

Description

Fmoc-NH-PEG6-CH2COOH features a C6 polyethylene glycol spacer flanked by a protective Fmoc group and a carboxylic acid terminus, enabling efficient conjugation in peptide synthesis. This bifunctional linker integrates seamlessly into solid-phase workflows, offering enhanced solubility and stability during chain elongation.

Application

Fmoc-NH-PEG6-CH2COOH serves as a versatile bifunctional linker for peptide synthesis and conjugation workflows. The Fmoc group enables orthogonal protection during solid-phase peptide synthesis, while the PEG6 spacer provides enhanced solubility and reduced aggregation. The terminal carboxylic acid facilitates amide coupling or activation for bioconjugation, offering reliable performance in antibody-drug conjugates and peptide-based therapeutics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   131.01
  • LogP   2.7093
  • H_Acceptors   9
  • H_Donors   2
  • Rotatable_Bonds   22

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