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Structure of 428452-50-0
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Methyl 3-amino-2,2-difluoropropanoate hydrochloride features a trifluoromethyl-like electronic profile with a labile amino group, enabling direct incorporation into peptide-like scaffolds. The hydrochloride salt enhances solubility and stability in polar solvents, simplifying handling during synthetic workflows. This building block integrates efficiently into fluorinated amine architectures for medicinal chemistry applications.
Methyl 3-amino-2,2-difluoropropanoate hydrochloride serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated amino acid derivatives and bioactive heterocycles. Its difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the amine functionality facilitates straightforward derivatization. The hydrochloride salt improves bench stability and simplifies purification, making it well-suited for scalable peptide and small-molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: