Methyl 5-aminopicolinate

Name: Methyl 5-aminopicolinate
Brand: ChemScene
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CAS No. 67515-76-8
Cat. No. CS-W009245
Purity≥95%
MDL No.MFCD07783939

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 67515-76-8

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Description

Methyl 5-aminopicolinate features a pyridine ring bearing both methyl ester and primary amine functionalities. This dual functionality enables direct incorporation into peptide conjugation workflows or as a precursor for heterocyclic synthesis. The para-amine group enhances solubility in polar solvents and supports further derivatization under mild conditions.

Application

Methyl 5-aminopicolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles and bioactive scaffolds. The ortho-amino and ester functionalities offer complementary reactivity for selective functionalization, including coupling reactions and cyclization pathways. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward purification and integration into multi-step syntheses.

General Information

CAS No. 67515-76-8
Cat. No. CS-W009245
Purity ≥95%
MDL No. MFCD07783939
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₂O₂
Molecular Weight 152.15
Synonym(s) Methyl 5-aminopyridine-2-carboxylate
SMILES O=C(C1=NC=C(N)C=C1)OC

Computational Chemistry Data

TPSA 65.21
LogP 0.4504
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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Methyl 5-aminopicolinate

CAS No. 67515-76-8

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