Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Amino-2,2-difluoropropanoic acid hydrochloride

  • CAS No. 1159825-06-5

  • Cat. No. CS-W000458
  • Purity≥98%
  • MDL No.MFCD11501119

*For research and further manufacturing use only, not for direct human use.

3-Amino-2,2-difluoropropanoic acid hydrochloride|CS-W000458

Structure of 1159825-06-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1159825-06-5
  • Cat. No. CS-W000458
  • Purity ≥98%
  • MDL No. MFCD11501119
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆ClF₂NO₂
  • Molecular Weight 161.54
  • Synonym(s) 3-Amino-2,2-difluoro-propionic acid hydrochloride
  • SMILES Cl.NCC(F)(F)C(O)=O

Description

This hydrochloride salt delivers a stable, moisture-tolerant source of 3-amino-2,2-difluoropropanoic acid, featuring a sterically hindered difluoromethyl group and a protonated amino function. The zwitterionic character enhances solubility in aqueous systems, enabling direct incorporation into peptide synthesis workflows under standard conditions.

Application

3-Amino-2,2-difluoropropanoic acid hydrochloride serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated amino acid derivatives with enhanced metabolic stability. The difluoromethyl group imparts favorable lipophilicity and resistance to oxidative metabolism, while the protonated amine facilitates salt formation and improves solubility for downstream conjugation. Its robust bench stability and compatibility with standard coupling protocols make it ideal for peptide extension and heterocyclic scaffold elaboration in API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.0868
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1159825-06-5 sigma1159825-06-5 manufacturer1159825-06-5 price1159825-06-5 structure1159825-06-5 SDSbuy 1159825-06-51159825-06-5 supplier1159825-06-5 uses1159825-06-5 molecular weightprice of 1159825-06-51159825-06-5 chemical name formula of 1159825-06-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label