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CS-W001157 4
Total: USD 88.00

Benzyl-PEG7-alcohol

  • CAS No. 423763-19-3

  • Cat. No. CS-0147665
  • Purity≥95%
  • MDL No.MFCD24682795

*For research and further manufacturing use only, not for direct human use.

Benzyl-PEG7-alcohol|CS-0147665

Structure of 423763-19-3

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General Information

  • CAS No. 423763-19-3
  • Cat. No. CS-0147665
  • Purity ≥95%
  • MDL No. MFCD24682795
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₃₆O₈
  • Molecular Weight 416.51
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCCOCCOCCOCC1=CC=CC=C1

Description

Benzyl-PEG7-alcohol features a hydrophilic PEG7 chain terminating in a primary alcohol, enabling conjugation or derivatization. The benzyl group enhances solubility and stability in organic solvents, making it ideal for synthesizing bioconjugates, drug delivery systems, and functionalized surfaces under standard conditions.

Application

Benzyl-PEG7-alcohol serves as a versatile, bench-stable linker for the synthesis of bioconjugates and functionalized polymers. Its terminal hydroxyl group enables straightforward derivatization via esterification or etherification, while the PEG7 spacer provides enhanced solubility and reduced aggregation. The benzyl moiety offers orthogonal protection and facilitates purification through standard chromatographic techniques. This compound functions effectively in peptide modification, drug delivery systems, and surface functionalization workflows.

Synthesis

  • Route1
    • In-stock
      Benzyl-PEG3-MS|CS-0148539
      702701-70-0
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • ~49%
    • In-stock
      Benzyl-PEG7-alcohol|CS-0147665
      423763-19-3

    References

    • James, Kenneth D. Patent: US2008/207505 A1, 2008 ; Location in patent: Page/Page column 32 ;
  • Route2
    • Benzyl-PEG7-THP|CS-0148535
      230620-75-4
    • ~99%
    • In-stock
      Benzyl-PEG7-alcohol|CS-0147665
      423763-19-3

    References

    • Burns, Christopher J.; Field, Leslie D.; Morgan, Jacqueline; Petteys, Brian J.; Prashar, Jognandan; Ridley, Damon D.; Sandanayake, K.R.A. Samankumara; Vignevich, Valentina Australian Journal of Chemistry, 2001 , vol. 54, # 7 p. 431 - 438
  • Route3
    • null|null
      1144113-13-2
    • ~%
    • In-stock
      Benzyl-PEG8-alcohol|CS-0147740
      477775-73-8
    • In-stock
      Benzyl-PEG7-alcohol|CS-0147665
      423763-19-3

    References

    • French, Alister C.; Thompson, Amber L.; Davis, Benjamin G. Angewandte Chemie - International Edition, 2009 , vol. 48, # 7 p. 1248 - 1252

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   84.84
  • LogP   1.2951
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   22

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