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CS-W001157 4
Total: USD 88.00

m-PEG7-alcohol

  • CAS No. 4437-01-8

  • Cat. No. CS-0114725
  • Purity≥96%
  • MDL No.MFCD06201006

*For research and further manufacturing use only, not for direct human use.

m-PEG7-alcohol|CS-0114725

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General Information

  • CAS No. 4437-01-8
  • Cat. No. CS-0114725
  • Purity ≥96%
  • MDL No. MFCD06201006
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₂O₈
  • Molecular Weight 340.41
  • Synonym(s) O-Methyl-heptaethylene glycol
  • SMILES COCCOCCOCCOCCOCCOCCOCCO

Description

m-PEG7-alcohol features a linear, hydrophilic poly(ethylene glycol) chain with seven ethylene oxide units, terminating in a primary alcohol group. This functionalized PEG derivative offers enhanced solubility in aqueous and polar organic media, enabling seamless integration into conjugation workflows. The terminal OH group facilitates straightforward derivatization for bioconjugation or surface modification applications.

Application

m-PEG7-alcohol serves as a versatile, bench-stable linker for conjugation and solubilization in synthetic chemistry. Its terminal hydroxyl group enables straightforward functionalization via esterification, etherification, or activation for amide bond formation. The polyethylene glycol (PEG) chain provides excellent aqueous solubility and reduced non-specific binding, making it ideal for constructing bioconjugates, prodrug intermediates, and polar scaffolds in medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • Ekwuribe, Nnochiri N.; Price, Christopher H.; Ansari, Aslam M.; Odenbaugh, Amy L. Patent: US2003/228275 A1, 2003 ; Location in patent: Page 40 ;
  • Route2
    • In-stock
      m-PEG3-OMs|CS-0114936
      74654-05-0
    • null|null
      68999-61-1
    • ~82%
    • In-stock
      m-PEG7-alcohol|CS-0114725
      4437-01-8

    References

    • Soltero, Richard; Radhakrishnan, Balasingam; Ekwuribe, Nnochiri N. Patent: US2003/229009 A1, 2003 ; Location in patent: Page 41 ;
  • Route3
    • In-stock
      Hexaethylene glycol|CS-0115001
      2615-15-8
    • null|null
      6482-24-2
    • ~39%
    • In-stock
      m-PEG7-alcohol|CS-0114725
      4437-01-8

    References

    • Bentley, Michael D.; Viegas, Tacey X.; Goodin, Richard R.; Cheng, Lin; Zhao, Xuan Patent: US2005/136031 A1, 2005 ; Location in patent: Page/Page column 25 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.84
  • LogP   -0.2753
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   20

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