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CS-W001157 4
Total: USD 88.00

BnO-PEG5-OH

  • CAS No. 57671-28-0

  • Cat. No. CS-0035717
  • Purity≥95%
  • MDL No.MFCD06797154

*For research and further manufacturing use only, not for direct human use.

BnO-PEG5-OH|CS-0035717

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General Information

  • CAS No. 57671-28-0
  • Cat. No. CS-0035717
  • Purity ≥95%
  • MDL No. MFCD06797154
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈O₆
  • Molecular Weight 328.40
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCCOCC1=CC=CC=C1

Description

BnO-PEG5-OH is a hydrophilic, bench-stable PEG-based linker featuring a benzyl ether protecting group and terminal hydroxyl functionality. This structure enables reliable conjugation in peptide synthesis and bioconjugation workflows, offering enhanced solubility and compatibility with aqueous and organic media.

Application

BnO-PEG5-OH serves as a versatile, bench-stable linker for the synthesis of functionalized polymers and bioconjugates. Its terminal hydroxyl group enables straightforward derivatization, while the benzyloxy-protected PEG5 chain offers excellent solubility and stability. The molecule facilitates efficient coupling reactions with carboxylic acids and amines, making it ideal for constructing complex architectures in medicinal chemistry and materials science workflows.

Synthesis

  • Route1
    • In-stock
      Pentaethylene glycol|CS-W007341
      4792-15-8
    • null|null
      100-44-7
    • ~81%
    • In-stock
      BnO-PEG5-OH|CS-0035717
      57671-28-0

    References

    • Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822
  • Route2
    • In-stock
      Pentaethylene glycol|CS-W007341
      4792-15-8
    • null|null
      100-39-0
    • ~65%
    • In-stock
      BnO-PEG5-OH|CS-0035717
      57671-28-0

    References

    • Renkes, Tanja; Schaefer, Hans J.; Siemens, Peter M.; Neumann, Eberhard Angewandte Chemie (International Edition in English), 2000 , vol. 39, # 14 p. X2512-2516
  • Route3

    References

    • Synthetic Communications, , vol. 29, # 13 p. 2337 - 2347

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.38
  • LogP   1.2619
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   16

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