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CS-W001157 4
Total: USD 88.00

BnO-PEG4-OH

  • CAS No. 86259-87-2

  • Cat. No. CS-W020968
  • Purity≥96%
  • MDL No.MFCD06797175

*For research and further manufacturing use only, not for direct human use.

BnO-PEG4-OH|CS-W020968

Structure of 86259-87-2

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General Information

  • CAS No. 86259-87-2
  • Cat. No. CS-W020968
  • Purity ≥96%
  • MDL No. MFCD06797175
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₄O₅
  • Molecular Weight 284.35
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCC1=CC=CC=C1

Description

BnO-PEG4-OH is a water-soluble, bench-stable linker featuring a benzyl ether-protected hydroxyl group at one terminus and a terminal hydroxyl at the other. This dual-functional architecture enables efficient conjugation in synthetic workflows, particularly in peptide modification and bioconjugation applications where orthogonal protection strategies are required.

Application

BnO-PEG4-OH serves as a versatile, bench-stable linker for the construction of bioconjugates and functionalized polymers. Its terminal hydroxyl group enables straightforward derivatization via esterification or ether formation, while the benzyloxy-protected PEG4 chain offers excellent solubility and controlled hydrophilicity. This compound functions as a reliable spacer in peptide modification, glycoconjugate synthesis, and the preparation of polymeric drug delivery systems.

Synthesis

  • Route1
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • null|null
      100-39-0
    • ~94%
    • In-stock
      BnO-PEG4-OH|CS-W020968
      86259-87-2

    References

    • WO2008/54466 A2, ; Page/Page column 32-33 ;
  • Route2
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • null|null
      100-44-7
    • ~85%
    • In-stock
      BnO-PEG4-OH|CS-W020968
      86259-87-2

    References

    • Synthetic Communications, , vol. 20, # 6 p. 799 - 807
  • Route3
    • null|null
      100-39-0
    • ~89%
    • In-stock
      BnO-PEG4-OH|CS-W020968
      86259-87-2

    References

    • WO2007/112100 A2, ; Page/Page column 44; 103; 110; 128; 130; 138 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.15
  • LogP   1.2453
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   13

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