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CS-W001157 4
Total: USD 88.00

2,3,3-Trimethyl-3H-indol-5-ol

  • CAS No. 41797-88-0

  • Cat. No. CS-0617004
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,3,3-Trimethyl-3H-indol-5-ol|CS-0617004

Structure of 41797-88-0

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Description

2,3,3-Trimethyl-3H-indol-5-ol features a sterically hindered indole core with a phenolic hydroxyl group at C5, enabling direct functionalization in synthetic routes. The methyl substituents enhance stability and solubility in organic media, while the electron-rich system supports efficient coupling reactions under mild conditions. This scaffold serves as a key building block for bioactive heterocycles.

Application

2,3,3-Trimethyl-3H-indol-5-ol serves as a versatile building block for indole-based scaffolds, offering enhanced stability and solubility compared to unsubstituted analogs. Its phenolic hydroxyl group enables direct derivatization via etherification or esterification, while the C3-trimethyl substitution prevents unwanted side reactions at the pyrrole nitrogen. The molecule functions effectively in coupling reactions and facilitates access to biologically relevant heterocycles under standard synthetic conditions.

General Information

  • CAS No. 41797-88-0
  • Cat. No. CS-0617004
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₃NO
  • Molecular Weight 175.23
  • Synonym(s) None
  • SMILES OC1=CC2=C(N=C(C)C2(C)C)C=C1

Computational Chemistry Data

  • TPSA   32.59
  • LogP   2.7758
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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