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Structure of 41797-88-0
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2,3,3-Trimethyl-3H-indol-5-ol features a sterically hindered indole core with a phenolic hydroxyl group at C5, enabling direct functionalization in synthetic routes. The methyl substituents enhance stability and solubility in organic media, while the electron-rich system supports efficient coupling reactions under mild conditions. This scaffold serves as a key building block for bioactive heterocycles.
2,3,3-Trimethyl-3H-indol-5-ol serves as a versatile building block for indole-based scaffolds, offering enhanced stability and solubility compared to unsubstituted analogs. Its phenolic hydroxyl group enables direct derivatization via etherification or esterification, while the C3-trimethyl substitution prevents unwanted side reactions at the pyrrole nitrogen. The molecule functions effectively in coupling reactions and facilitates access to biologically relevant heterocycles under standard synthetic conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: