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CS-W001157 4
Total: USD 88.00

N-(2-Hydroxyethyl)hexamethyleneimine

  • CAS No. 20603-00-3

  • Cat. No. CS-B0251
  • Molecule weight143.23
  • Purity≥98%
  • MDL No.MFCD00020988

*For research and further manufacturing use only, not for direct human use.

N-(2-Hydroxyethyl)hexamethyleneimine|CS-B0251

Structure of 20603-00-3

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General Information

  • CAS No. 20603-00-3
  • Cat. No. CS-B0251
  • Purity ≥98%
  • MDL No. MFCD00020988
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO
  • Molecular Weight 143.23
  • Synonym(s) N-(2-hydroxyethyl)hexahydro-1H-azepine
  • SMILES OCCN1CCCCCC1

Description

N-(2-Hydroxyethyl)hexamethyleneimine features a hydroxyl-functionalized side chain appended to a six-membered cyclic amine, enabling dual reactivity in polymer synthesis. This bifunctional architecture facilitates efficient coupling with diisocyanates and epoxides, delivering crosslinked networks with enhanced hydrophilicity and thermal stability. The pendant hydroxyl group improves solubility in polar solvents and supports further derivatization under mild conditions.

Application

N-(2-Hydroxyethyl)hexamethyleneimine serves as a versatile bifunctional building block, enabling efficient conjugation via its primary amine and hydroxyl groups. It functions as a key intermediate in the synthesis of polymeric materials and bioactive molecules, offering excellent solubility and stability under standard reaction conditions. Its cyclic imine structure facilitates controlled reactivity in nucleophilic addition and ring-opening processes, supporting reliable functionalization for advanced chemical scaffolds.

Synthesis

  • Route1
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    • In-stock
      N-(2-Hydroxyethyl)hexamethyleneimine|CS-B0251
      20603-00-3

    References

    • Zhurnal Obshchei Khimii, , vol. 27, p. 458;engl.Ausg.S.517 US2735847 , ; US2743269 , ; Journal of the American Chemical Society, , vol. 77, p. 1565,1566
  • Route2
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      1072-21-5
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      141-43-5
    • ~56%
    • In-stock
      N-(2-Hydroxyethyl)hexamethyleneimine|CS-B0251
      20603-00-3

    References

    • Journal of Heterocyclic Chemistry, , vol. 25, p. 1383 - 1385
  • Route3
    • null|null
      111-49-9
    • null|null
      540-51-2
    • ~%
    • In-stock
      N-(2-Hydroxyethyl)hexamethyleneimine|CS-B0251
      20603-00-3

    References

    • Zhurnal Obshchei Khimii, , vol. 29, p. 631,632; engl. Ausg. S. 626, 627

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   0.8547
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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