2-Bromo-4-(4-fluorophenyl)-1,3-thiazole

Name: 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 412923-44-5
Cat. No. CS-0072321
Purity≥95%
MDL No.MFCD07375244

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-4-(4-fluorophenyl)-1,3-thiazole|CS-0072321

Structure of 412923-44-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 412923-44-5
Cat. No. CS-0072321
Purity ≥95%
MDL No. MFCD07375244
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₅BrFNS
Molecular Weight 258.11
Synonym(s) 2-BROMO-4-(4-FLUORO-PHENYL)-THIAZOLE
SMILES BrC1=NC(C2=CC=C(F)C=C2)=CS1

Description

2-Bromo-4-(4-fluorophenyl)-1,3-thiazole features a brominated thiazole core flanked by a para-fluorophenyl substituent, delivering enhanced reactivity in cross-coupling transformations. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, offering a robust platform for diversification via palladium-catalyzed reactions.

Application

2-Bromo-4-(4-fluorophenyl)-1,3-thiazole serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the 4-fluorophenyl group enhances electronic modulation and metabolic stability. The molecule exhibits bench stability and facilitates efficient functionalization in standard synthetic workflows, making it well-suited for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Synthesis

Route1
- 43045-16-5
- ~92%
- In-stock
  
  412923-44-5
References
- Kono, Mitsunori; Matsumoto, Takahiro; Kawamura, Toru; Nishimura, Atsushi; Kiyota, Yoshihiro; Oki, Hideyuki; Miyazaki, Junichi; Igaki, Shigeru; Behnke, Craig A.; Shimojo, Masato; Kori, Masakuni Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 1 p. 28 - 41
Route2
- In-stock
  
  403-29-2
- ~%
- In-stock
  
  412923-44-5
References
- Li, Wen-Tai; Wu, Wan-Hsun; Tang, Chien-Hsiang; Tai, Ready; Chen, Shui-Tein ACS Combinatorial Science, 2011 , vol. 13, # 1 p. 72 - 78
Route3
- In-stock
  
  403-42-9
- ~%
- In-stock
  
  412923-44-5
References
- Li, Wen-Tai; Wu, Wan-Hsun; Tang, Chien-Hsiang; Tai, Ready; Chen, Shui-Tein ACS Combinatorial Science, 2011 , vol. 13, # 1 p. 72 - 78

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 12.89
LogP 3.7117
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Bromo-4-(4-fluorophenyl)-1,3-thiazole sigma2-Bromo-4-(4-fluorophenyl)-1,3-thiazole manufacturer2-Bromo-4-(4-fluorophenyl)-1,3-thiazole price2-Bromo-4-(4-fluorophenyl)-1,3-thiazole structure2-Bromo-4-(4-fluorophenyl)-1,3-thiazole SDSbuy 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole2-Bromo-4-(4-fluorophenyl)-1,3-thiazole supplier2-Bromo-4-(4-fluorophenyl)-1,3-thiazole uses2-Bromo-4-(4-fluorophenyl)-1,3-thiazole molecular weightprice of 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole2-Bromo-4-(4-fluorophenyl)-1,3-thiazole chemical name formula of 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-4-(4-fluorophenyl)-1,3-thiazole

CAS No. 412923-44-5

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words