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Structure of 41162-19-0
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Dimethyl (2-oxo-4-phenylbutyl)phosphonate features a β-keto phosphonate moiety flanked by a phenyl-substituted alkyl chain, enabling direct C–C bond formation via Horner-Wadsworth-Emmons reactions. This bench-stable reagent delivers high stereoselectivity in olefination processes and integrates readily into complex molecular architectures under mild conditions.
Dimethyl (2-oxo-4-phenylbutyl)phosphonate serves as a versatile synthon in C–C bond formation, enabling efficient access to β-keto phosphonate derivatives via aldol-type reactions. Its α,β-unsaturated carbonyl motif facilitates conjugate addition and Michael-type processes, while the phosphonate group supports Stobbe condensations and Horner–Wadsworth–Emmons olefination. The molecule exhibits good bench stability and tolerates common functional groups, making it a practical building block for complex heterocyclic and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: