Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Diethyl (difluoromethyl)phosphonate

  • CAS No. 1478-53-1

  • Cat. No. CS-0094054
  • Molecule weight188.11
  • Purity≥97%
  • MDL No.MFCD00192023

*For research and further manufacturing use only, not for direct human use.

Diethyl (difluoromethyl)phosphonate|CS-0094054

Structure of 1478-53-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1478-53-1
  • Cat. No. CS-0094054
  • Purity ≥97%
  • MDL No. MFCD00192023
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁F₂O₃P
  • Molecular Weight 188.11
  • Synonym(s) uoromethanephosphonate
  • SMILES O=P(OCC)(C(F)F)OCC

Description

Diethyl (difluoromethyl)phosphonate features a difluoromethyl group tethered to a phosphonate core, delivering enhanced electrophilicity and stability. This bench-stable reagent integrates readily into C–H functionalization and cross-coupling protocols, enabling efficient construction of fluorinated building blocks under mild conditions.

Synthesis

  • Route1
    • null|null
      75-45-6
    • null|null
      762-04-9
    • ~86%
    • In-stock
      Diethyl (difluoromethyl)phosphonate|CS-0094054
      1478-53-1

    References

    • Pignard, Sebastien; Lopin, Chrystel; Gouhier, Geraldine; Piettre, Serge R. Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 31 - 37
  • Route2
    • null|null
      58310-30-8
    • null|null
      122-52-1
    • ~15%
    • In-stock
      Diethyl (difluoromethyl)phosphonate|CS-0094054
      1478-53-1
    • null|null
      7549-83-9

    References

    • Flynn, Richard M.; Burton, Donald J. Journal of Fluorine Chemistry, 2011 , vol. 132, # 10 p. 815 - 828
  • Route3

    References

    • MERRELL DOW PHARMACEUTICALS INC. Patent: EP339161 A1, 1989 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.53
  • LogP   2.4751
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Diethyl (difluoromethyl)phosphonate sigmaDiethyl (difluoromethyl)phosphonate manufacturerDiethyl (difluoromethyl)phosphonate priceDiethyl (difluoromethyl)phosphonate structureDiethyl (difluoromethyl)phosphonate SDSbuy Diethyl (difluoromethyl)phosphonateDiethyl (difluoromethyl)phosphonate supplierDiethyl (difluoromethyl)phosphonate usesDiethyl (difluoromethyl)phosphonate molecular weightprice of Diethyl (difluoromethyl)phosphonateDiethyl (difluoromethyl)phosphonate chemical name formula of Diethyl (difluoromethyl)phosphonate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label