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CS-W001157 4
Total: USD 88.00

1,2-Bis(4-fluorophenyl)disulfane

  • CAS No. 405-31-2

  • Cat. No. CS-0128788
  • Purity≥97%
  • MDL No.MFCD00816758

*For research and further manufacturing use only, not for direct human use.

1,2-Bis(4-fluorophenyl)disulfane|CS-0128788

Structure of 405-31-2

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General Information

  • CAS No. 405-31-2
  • Cat. No. CS-0128788
  • Purity ≥97%
  • MDL No. MFCD00816758
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈F₂S₂
  • Molecular Weight 254.32
  • Synonym(s) disulfide, bis(4-fluorophenyl)
  • SMILES FC1=CC=C(SSC2=CC=C(F)C=C2)C=C1

Description

Acid-PEG5-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Synthesis

  • Route1

    References

    • Alam, Ashraful; Takaguchi, Yutaka; Tsuboi, Sadao Synthetic Communications, 2005 , vol. 35, # 10 p. 1329 - 1333
  • Route2

    References

    • Zhao, Qian; Qian, Chao; Chen, Xin-Zhi Monatshefte fur Chemie, 2013 , vol. 144, # 10 p. 1547 - 1550
  • Route3

    References

    • JMC CORPORATION Patent: WO2007/66844 A1, 2007 ; Location in patent: Page/Page column 13-14 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.7642
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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