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CS-W001157 4
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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)propanoic acid

  • CAS No. 852288-18-7

  • Cat. No. CS-0101058
  • Purity≥97%
  • MDL No.MFCD08064332

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)propanoic acid|CS-0101058

Structure of 852288-18-7

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General Information

  • CAS No. 852288-18-7
  • Cat. No. CS-0101058
  • Purity ≥97%
  • MDL No. MFCD08064332
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₂₅NO₆
  • Molecular Weight 459.49
  • Synonym(s) FMOC-DOPA(ACETONIDE)-OH
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC4=CC(OC(C)(C)O5)=C5C=C4

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)propanoic acid features a sterically hindered benzo[1,3]dioxole moiety that enhances stability and solubility in organic solvents. This protected amino acid derivative integrates seamlessly into solid-phase peptide synthesis workflows, offering high coupling efficiency and minimal racemization under standard conditions.

Synthesis

  • Route1

    References

    • US8227628 B2, ;
  • Route2
    • null|null
      297144-73-1
    • ~%
    • In-stock
      (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)propanoic acid|CS-0101058
      852288-18-7

    References

    • US8227628 B2, ;
  • Route3
    • null|null
      1064196-07-1
    • ~%
    • In-stock
      (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)propanoic acid|CS-0101058
      852288-18-7

    References

    • US8227628 B2, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   94.09
  • LogP   4.7283
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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