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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid

  • CAS No. 184962-88-7

  • Cat. No. CS-0101043
  • Purity≥98%
  • MDL No.MFCD01317730

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid|CS-0101043

Structure of 184962-88-7

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General Information

  • CAS No. 184962-88-7
  • Cat. No. CS-0101043
  • Purity ≥98%
  • MDL No. MFCD01317730
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₅NO₆
  • Molecular Weight 447.48
  • Synonym(s) Fmoc-3,4-dimethoxy-L-phenylalanine
  • SMILES O=C(O)[C@H](CC1=CC(OC)=C(C=C1)OC)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid is a chiral building block featuring a fluorenylmethoxycarbonyl (Fmoc) protected amino group and a sterically hindered aromatic side chain. This configuration enables efficient incorporation into peptide sequences under mild coupling conditions, with the Fmoc group offering high stability and clean deprotection. The dimethoxyphenyl moiety enhances solubility and provides a distinct chromophoric handle for analytical monitoring.

Synthesis

  • Route1
    • (S)-2-Amino-3-(3,4-dimethoxyphenyl)propionic acid Levodopa  Impurity|CS-0229474
      32161-30-1
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • ~94%
    • In-stock
      (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid|CS-0101043
      184962-88-7

    References

    • Journal of Organic Chemistry, , vol. 61, # 25 p. 8940 - 8948

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
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UN#: N/A
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Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   94.09
  • LogP   4.2382
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   8

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