Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid

Name: Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid
Brand: ChemScene
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CAS No. 270063-38-2
Cat. No. CS-0062186
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid|CS-0062186

Structure of 270063-38-2

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Description

Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid is a specialized amino acid derivative featuring a naphthyl group that enhances π-stacking interactions in peptide design. This bulky, electron-rich side chain improves structural rigidity and hydrophobic character, ideal for stabilizing bioactive conformations in peptidomimetics. The Fmoc protecting group ensures compatibility with standard solid-phase peptide synthesis protocols.

Application

Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid serves as a versatile building block for the synthesis of peptide-based scaffolds and bioactive molecules. The Fmoc group enables efficient solid-phase peptide synthesis, while the naphthyl moiety imparts structural rigidity and enhanced hydrophobicity. This amino acid derivative exhibits excellent bench stability, tolerates standard coupling conditions, and facilitates purification via common chromatographic methods. It is particularly valuable for constructing peptidomimetics and heterocyclic systems requiring aromatic side-chain functionality.

General Information

CAS No. 270063-38-2
Cat. No. CS-0062186
Purity ≥95%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₉H₂₅NO₄
Molecular Weight 451.51
Synonym(s) None
SMILES O=C(O)C[C@@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)CC4=CC=CC5=CC=CC=C54

Computational Chemistry Data

TPSA 75.63
LogP 5.7643
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic ring compounds Naphthalene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid

CAS No. 270063-38-2

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