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CS-W001157 4
Total: USD 88.00

4-Bromo-6-methoxy-1H-indole

  • CAS No. 393553-55-4

  • Cat. No. CS-W022112
  • Purity≥96%
  • MDL No.MFCD03095207

*For research and further manufacturing use only, not for direct human use.

4-Bromo-6-methoxy-1H-indole|CS-W022112

Structure of 393553-55-4

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General Information

  • CAS No. 393553-55-4
  • Cat. No. CS-W022112
  • Purity ≥96%
  • MDL No. MFCD03095207
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BrNO
  • Molecular Weight 226.07
  • Synonym(s) 4-broMo-6-Methyloxyl indole
  • SMILES COC1=CC2=C(C(Br)=C1)C=CN2

Description

4-Bromo-6-methoxy-1H-indole features a bromine substituent at the 4-position and a methoxy group at the 6-position, conferring enhanced electronic modulation and improved solubility in organic media. This indole scaffold serves as a key building block for bioactive heterocycles, particularly in medicinal chemistry and agrochemical development.

Application

4-Bromo-6-methoxy-1H-indole serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic bromine site. The 6-methoxy group enhances solubility and modulates electronic properties, while the indole core provides a robust scaffold for heterocyclic diversification. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to complex molecular architectures.

Safety Information

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Computational Chemistry Data

  • TPSA   25.02
  • LogP   2.939
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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