5-Bromo-3-chloro-2-fluoropyridine

Name: 5-Bromo-3-chloro-2-fluoropyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 38185-56-7
Cat. No. CS-W003656
Purity≥97%
MDL No.MFCD09834365

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-chloro-2-fluoropyridine|CS-W003656

Structure of 38185-56-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 38185-56-7
Cat. No. CS-W003656
Purity ≥97%
MDL No. MFCD09834365
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂BrClFN
Molecular Weight 210.43
Synonym(s) 2-Fluoro-3-Chloro-5-Bromopyridine
SMILES Brc1cnc(c(c1)Cl)F

Description

5-Bromo-3-chloro-2-fluoropyridine is a halogenated pyridine scaffold featuring strategically positioned bromo, chloro, and fluoro substituents. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions and serves as a key intermediate in medicinal chemistry. The combination of orthogonal reactive halogens allows sequential functionalization under mild conditions.

Application

5-Bromo-3-chloro-2-fluoropyridine serves as a versatile trifunctional pyridine building block for cross-coupling and heterocyclic synthesis. Its orthogonal halogen reactivity enables sequential Pd-catalyzed transformations, facilitating the construction of complex pharmaceutical scaffolds. The compound exhibits excellent bench stability and compatibility with standard reaction conditions, simplifying purification and scale-up in medicinal chemistry campaigns.

Synthesis

Route1
- In-stock
  
  38185-55-6
- ~85%
- In-stock
  
  38185-56-7
References
- Banyu Pharmaceutical Co., Ltd. Patent: EP2221301 A1, 2010 ; Location in patent: Page/Page column 46 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 12.89
LogP 2.6366
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

5-Bromo-3-chloro-2-fluoropyridine sigma5-Bromo-3-chloro-2-fluoropyridine manufacturer5-Bromo-3-chloro-2-fluoropyridine price5-Bromo-3-chloro-2-fluoropyridine structure5-Bromo-3-chloro-2-fluoropyridine SDSbuy 5-Bromo-3-chloro-2-fluoropyridine5-Bromo-3-chloro-2-fluoropyridine supplier5-Bromo-3-chloro-2-fluoropyridine uses5-Bromo-3-chloro-2-fluoropyridine molecular weightprice of 5-Bromo-3-chloro-2-fluoropyridine5-Bromo-3-chloro-2-fluoropyridine chemical name formula of 5-Bromo-3-chloro-2-fluoropyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-3-chloro-2-fluoropyridine

CAS No. 38185-56-7

Recommended Products