Lot numbers can be found on the outside label of a product:
2-Ethynylpyrimidine
-
CAS No. 37972-24-0
- Cat. No. CS-W019045
- Purity≥97%
- MDL No.MFCD10698134
*For research and further manufacturing use only, not for direct human use.
Structure of 37972-24-0
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 37972-24-0
- Cat. No. CS-W019045
- Purity ≥97%
- MDL No. MFCD10698134
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₄N₂
- Molecular Weight 104.11
- Synonym(s) Pyrimidine, 2-ethynyl- (9CI)
- SMILES C(#C)C1=NC=CC=N1
Description
2-Ethynylpyrimidine delivers a reactive alkyne handle within a nitrogen-rich heterocyclic framework, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials functionalization. This bench-stable, moisture-tolerant reagent integrates seamlessly into modular synthesis workflows.
Application
2-Ethynylpyrimidine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed coupling reactions such as Sonogashira and Suzuki-Miyaura transformations. Its terminal alkyne functionality exhibits excellent stability under standard reaction conditions and facilitates efficient access to functionalized pyrimidine scaffolds commonly found in pharmaceutical and agrochemical intermediates. The molecule demonstrates broad compatibility with diverse functional groups and supports straightforward purification, making it well-suited for iterative synthesis and library development.
Synthesis
-
Route1
-
193631-86-6 - ~%
-
In-stock
37972-24-0
References
-
Li, Tiehai; Guo, Lina; Zhang, Yan; Wang, Jiajia; Li, Zhonghua; Lin, Lin; Zhang, Zhenxing; Li, Lei; Lin, Jianping; Zhao, Wei; Li, Jing; Wang, Peng George Carbohydrate Research, 2011 , vol. 346, # 9 p. 1083 - 1092
-
-
Route2
-
193631-86-6
-
In-stock
54-42-2 - ~%
-
In-stock
37972-24-0
References
-
Gilead Sciences, Inc. Patent: US5645985 A1, 1997 ;
-
-
Route3
-
In-stock
4595-60-2 -
115-19-5
- ~4%
-
In-stock
37972-24-0
References
-
Lottermoser, Ursula; Rademacher, Paul; Mazik, Monika; Kowski, Klaus European Journal of Organic Chemistry, 2005 , # 3 p. 522 - 531
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H319
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 25.78
- LogP 0.4579
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 0
Similar Products
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-Ethynylpyrimidine sigma2-Ethynylpyrimidine manufacturer2-Ethynylpyrimidine price2-Ethynylpyrimidine structure2-Ethynylpyrimidine SDSbuy 2-Ethynylpyrimidine2-Ethynylpyrimidine supplier2-Ethynylpyrimidine uses2-Ethynylpyrimidine molecular weightprice of 2-Ethynylpyrimidine2-Ethynylpyrimidine chemical name formula of 2-Ethynylpyrimidine