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Structure of 5053-43-0
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2-Methylpyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and tunable basicity. Its electron-rich pyrimidine core facilitates efficient coupling reactions, while the methyl group provides steric guidance during functionalization. This compound integrates readily into kinase inhibitors and antiviral agents, delivering improved solubility and bioavailability in complex synthesis workflows.
2-Methylpyrimidine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its pyrimidine core provides a robust scaffold for C-H functionalization, metal-catalyzed coupling reactions, and derivatization at nitrogen sites. The methyl group enhances metabolic stability and facilitates selective transformations, while the compound exhibits good bench stability and ease of purification. Widely used in the construction of kinase inhibitors and nucleoside analogs, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H302-H315-H318-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: