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CS-W001157 4
Total: USD 88.00

2-Methylpyrimidine

  • CAS No. 5053-43-0

  • Cat. No. CS-W016665
  • Purity≥98%
  • MDL No.MFCD00128182
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Methylpyrimidine|CS-W016665

Structure of 5053-43-0

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Description

2-Methylpyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and tunable basicity. Its electron-rich pyrimidine core facilitates efficient coupling reactions, while the methyl group provides steric guidance during functionalization. This compound integrates readily into kinase inhibitors and antiviral agents, delivering improved solubility and bioavailability in complex synthesis workflows.

Application

2-Methylpyrimidine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its pyrimidine core provides a robust scaffold for C-H functionalization, metal-catalyzed coupling reactions, and derivatization at nitrogen sites. The methyl group enhances metabolic stability and facilitates selective transformations, while the compound exhibits good bench stability and ease of purification. Widely used in the construction of kinase inhibitors and nucleoside analogs, it functions reliably in standard synthetic workflows.

General Information

  • CAS No. 5053-43-0
  • Cat. No. CS-W016665
  • Purity ≥98%
  • MDL No. MFCD00128182
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂
  • Molecular Weight 94.12
  • Synonym(s) Pyrimidine, 2-methyl-
  • SMILES CC1=NC=CC=N1

Computational Chemistry Data

  • TPSA   25.78
  • LogP   0.78502
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group :
Hazard Statements : H226-H302-H315-H318-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501

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