(R)-1-(4-Fluorophenyl)ethylamine

Name: (R)-1-(4-Fluorophenyl)ethylamine
Brand: ChemScene
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CAS No. 374898-01-8
Cat. No. CS-D0231
Purity≥97%
MDL No.MFCD03093090

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-1-(4-Fluorophenyl)ethylamine|CS-D0231

Structure of 374898-01-8

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General Information

CAS No. 374898-01-8
Cat. No. CS-D0231
Purity ≥97%
MDL No. MFCD03093090
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀FN
Molecular Weight 139.17
Synonym(s) 1,1,1,2,2,3,3-heptafluoro-3-methoxypropane
SMILES N[C@H](C)C(C=C1)=CC=C1F

Description

(R)-1-(4-Fluorophenyl)ethylamine is a chiral building block featuring a fluorinated aromatic ring and a stereodefined amine group. This bench-stable, moisture-tolerant compound integrates readily into asymmetric synthesis workflows, enabling efficient access to enantiopure pharmaceutical intermediates through direct functionalization or coupling reactions.

Application

(R)-1-(4-Fluorophenyl)ethylamine serves as a chiral building block for pharmaceutical intermediates, enabling stereoselective synthesis of bioactive molecules. Its bench-stable nature and compatibility with common functional groups facilitate straightforward incorporation into diverse synthetic routes. The molecule functions effectively in asymmetric catalysis and as a precursor to arylalkylamine-containing APIs.

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07,GHS09
Signal Word : Danger	UN#: 2735
Class : 8	Packing Group : Ⅱ
Hazard Statements : H302-H314-H411
Precautionary Statements : P260-P264-P270-P273-P280-P301+P330+P331-P304+P340-P330-P363-P391-P405-P501

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Computational Chemistry Data

TPSA 26.02
LogP 1.8454
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(4-Fluorophenyl)ethylamine

CAS No. 374898-01-8

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