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Structure of 74788-44-6
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1-(2-Fluorophenyl)ethanamine features a fluorinated aromatic ring linked to an ethylamine side chain, delivering enhanced metabolic stability and improved membrane permeability. This configuration supports efficient integration into bioactive scaffolds for CNS-targeted therapeutics and synthetic intermediates. The ortho-fluoro substitution imparts directional electronic effects beneficial in transition metal-catalyzed coupling reactions.
1-(2-Fluorophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amine functionalization. Its fluorinated aryl group enhances metabolic stability and modulates electronic properties, while the primary amine facilitates conjugation reactions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: