(R)-1-(3-Fluorophenyl)ethanamine

Name: (R)-1-(3-Fluorophenyl)ethanamine
Brand: ChemScene
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CAS No. 761390-58-3
Cat. No. CS-0000301
Purity≥96%
MDL No.MFCD06761859

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(3-Fluorophenyl)ethanamine|CS-0000301

Structure of 761390-58-3

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General Information

CAS No. 761390-58-3
Cat. No. CS-0000301
Purity ≥96%
MDL No. MFCD06761859
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀FN
Molecular Weight 139.17
Synonym(s) (R)-3-Fluoro-alpha-methylbenzylamine
SMILES N[C@H](C)C1=CC(F)=CC=C1

Description

(R)-1-(3-Fluorophenyl)ethanamine is a chiral amine featuring a fluorinated phenyl ring that imparts enhanced metabolic stability and modulated lipophilicity. This configuration enables selective incorporation into bioactive molecules, particularly in CNS-targeted therapeutics and asymmetric synthesis intermediates. The bench-stable, moisture-tolerant structure simplifies handling in standard laboratory workflows.

Application

(R)-1-(3-Fluorophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of enantioselective pharmaceuticals. Its bench-stable nature and tolerance for diverse functional groups facilitate straightforward incorporation into target molecules via standard amine coupling and reduction protocols. The molecule functions effectively as a precursor for β-amino alcohol and amide derivatives, supporting scalable routes to bioactive scaffolds.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 26.02
LogP 1.8454
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(R)-1-(3-Fluorophenyl)ethanamine

CAS No. 761390-58-3

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