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CS-W001157 4
Total: USD 88.00

1-Boc-2-aminomethyl-piperidine

  • CAS No. 370069-31-1

  • Cat. No. CS-W020616
  • Molecule weight214.30
  • Purity≥98%
  • MDL No.MFCD01317791

*For research and further manufacturing use only, not for direct human use.

1-Boc-2-aminomethyl-piperidine|CS-W020616

Structure of 370069-31-1

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General Information

  • CAS No. 370069-31-1
  • Cat. No. CS-W020616
  • Purity ≥98%
  • MDL No. MFCD01317791
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂N₂O₂
  • Molecular Weight 214.30
  • Synonym(s) Tert-butyl 2-(aminomethyl)piperidine-1-carboxylate
  • SMILES O=C(OC(C)(C)C)N(CCCC1)C1CN

Description

1-Boc-2-aminomethyl-piperidine features a protected primary amine and a piperidine scaffold, enabling direct incorporation into peptide and small-molecule conjugates. The Boc group ensures stability during synthetic manipulations, while the pendant methylamine facilitates efficient derivatization under standard conditions.

Application

1-Boc-2-aminomethyl-piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of piperidine-based scaffolds through mild deprotection and subsequent functionalization. The Boc group provides excellent bench stability and compatibility with diverse reaction conditions, facilitating efficient incorporation into target molecules via amine coupling, reductive amination, or cyclization strategies. Its orthogonal functionality supports modular synthesis workflows common in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335-H410
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.7347
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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