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(1R,2R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid

  • CAS No. 359586-69-9

  • Cat. No. CS-0186029
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1R,2R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid|CS-0186029

Structure of 359586-69-9

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General Information

  • CAS No. 359586-69-9
  • Cat. No. CS-0186029
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₁NO₄
  • Molecular Weight 351.40
  • Synonym(s) (1R,2R)-FMOC-2-AMINOCYCLOPENTANE CARBOXYLIC ACID
  • SMILES O=C([C@H]1[C@H](NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)CCC1)O

Description

This fluorenylmethoxycarbonyl-protected cyclopentane derivative features a rigid, stereodefined scaffold ideal for peptide synthesis. The (1R,2R) configuration ensures precise spatial orientation, while the Fmoc group enables orthogonal deprotection under mild basic conditions. This combination supports high-yielding coupling reactions and facilitates purification in solid-phase workflows.

Synthesis

  • Route1

    References

    • Journal of Organic Chemistry, , vol. 66, # 16 p. 5629 - 5632

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.7784
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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