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CS-W001157 4
Total: USD 88.00

Fmoc-(S)-3-amino-3-(2-trifluoromethylphenyl)-propionic acid

  • CAS No. 507472-19-7

  • Cat. No. CS-0182709
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Fmoc-(S)-3-amino-3-(2-trifluoromethylphenyl)-propionic acid|CS-0182709

Structure of 507472-19-7

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General Information

  • CAS No. 507472-19-7
  • Cat. No. CS-0182709
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₀F₃NO₄
  • Molecular Weight 455.43
  • Synonym(s) Fmoc-S-3-Amino-3-(2-trifluoromethyl-phenyl)-propionic acid
  • SMILES O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](CC(O)=O)C4=C(C(F)(F)F)C=CC=C4

Description

Fmoc-(S)-3-amino-3-(2-trifluoromethylphenyl)-propionic acid is a sterically hindered, electron-deficient amino acid derivative designed for solid-phase peptide synthesis. The trifluoromethylphenyl group enhances lipophilicity and metabolic stability, while the Fmoc protecting group enables efficient sequential coupling under standard conditions. This building block facilitates incorporation of non-natural residues into bioactive peptides with improved membrane permeability and target engagement.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   5.7599
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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