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CS-W001157 4
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1-Methoxy-2-methyl-2-propanol

  • CAS No. 3587-64-2

  • Cat. No. CS-0186349
  • Purity≥98%
  • MDL No.MFCD03701584

*For research and further manufacturing use only, not for direct human use.

1-Methoxy-2-methyl-2-propanol|CS-0186349

Structure of 3587-64-2

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General Information

  • CAS No. 3587-64-2
  • Cat. No. CS-0186349
  • Purity ≥98%
  • MDL No. MFCD03701584
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂O₂
  • Molecular Weight 104.15
  • Synonym(s) 2-Methoxy-1,1-dimethylethanol
  • SMILES CC(C)(COC)O

Description

1-Methoxy-2-methyl-2-propanol is a tertiary alcohol solvent featuring a methoxy group and a methyl-substituted isopropyl backbone. This structure imparts excellent solubility for polar intermediates, enhanced stability under standard conditions, and low volatility. The molecule integrates readily into synthetic workflows requiring mild, non-nucleophilic reaction media.

Application

1-Methoxy-2-methyl-2-propanol serves as a stable, polar aprotic solvent and versatile synthetic intermediate. Its tertiary alcohol functionality enables facile etherification and protection strategies, while the methoxy group enhances solubility in both polar and nonpolar media. The molecule exhibits excellent bench stability, low volatility, and compatibility with a broad range of functional groups, facilitating clean reactions in multistep syntheses and enabling efficient workup procedures.

Synthesis

  • Route1

    References

    • US5663200 A1, ; US 5663200 A
  • Route2
    • In-stock
      1-Chloro-2-methyl-2-propanol|CS-0030576
      558-42-9
    • null|null
      124-41-4
    • ~%
    • In-stock
      1-Methoxy-2-methyl-2-propanol|CS-0186349
      3587-64-2

    References

    • Journal of the American Chemical Society, , vol. 75, p. 155,157
  • Route3

    References

    • Journal of Physical Organic Chemistry, , vol. 8, # 2 p. 121 - 126

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1987
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.4037
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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