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Structure of 349-02-0
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4-Fluoro-3-nitrobenzamide features a strategically positioned fluorine atom and nitro group on the benzene ring, enabling enhanced electron-withdrawing effects and directed functionalization. This combination supports efficient coupling reactions and facilitates incorporation into pharmaceutical scaffolds under standard conditions.
4-Fluoro-3-nitrobenzamide serves as a versatile building block in medicinal chemistry, enabling direct functionalization via nucleophilic aromatic substitution due to the ortho-fluorine relative to the electron-withdrawing nitro group. Its stability under standard reaction conditions and compatibility with diverse coupling protocols facilitate efficient access to substituted benzamides and heterocyclic scaffolds relevant to API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: