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Structure of 475216-25-2
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4-Fluoro-N-methyl-3-nitrobenzamide features a strategically positioned fluorine atom and nitro group on a benzamide scaffold, enabling enhanced electron-withdrawal and targeted reactivity. The N-methyl substitution improves metabolic stability and solubility, facilitating integration into pharmaceutical intermediates and complex molecular architectures under standard conditions.
4-Fluoro-N-methyl-3-nitrobenzamide serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds via standard coupling and cyclization protocols. The ortho-fluoro and nitro groups facilitate directed metallation and subsequent functionalization, while the N-methyl amide provides enhanced metabolic stability and favorable lipophilicity for drug-like molecules. Bench-stable and compatible with common reaction conditions, it supports scalable synthesis of bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: