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CS-W001157 4
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Methyl 4-hydroxypiperidine-2-carboxylate hydrochloride

  • CAS No. 337464-25-2

  • Cat. No. CS-0054210
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 4-hydroxypiperidine-2-carboxylate hydrochloride|CS-0054210

Structure of 337464-25-2

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General Information

  • CAS No. 337464-25-2
  • Cat. No. CS-0054210
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₃
  • Molecular Weight 195.64
  • Synonym(s) None
  • SMILES Cl.COC(=O)C1CC(O)CCN1

Description

Methyl 4-hydroxypiperidine-2-carboxylate hydrochloride features a bench-stable, moisture-tolerant piperidine core with a strategically positioned hydroxyl group enabling direct functionalization. This polar, nitrogen-rich scaffold integrates readily into synthetic sequences requiring controlled solubility and enhanced reactivity in medicinal chemistry applications.

Application

Methyl 4-hydroxypiperidine-2-carboxylate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to piperidine-based scaffolds. The hydroxyl and carboxylate functionalities offer orthogonal handles for derivatization, while the hydrochloride salt enhances solubility and stability under standard bench conditions. It functions effectively in amide coupling, glycosylation, and cyclization reactions, supporting robust synthetic workflows for drug discovery and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.3059
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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