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Structure of 31181-84-7
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(5-(Trifluoromethyl)pyridin-2-yl)methanol features a pyridine core bearing a trifluoromethyl group at the 5-position and a methylene alcohol function at the 2-position. This combination delivers enhanced electron-withdrawing character and improved solubility in polar solvents, enabling its use in transition-metal-catalyzed coupling reactions and as a building block for bioactive heterocycles.
(5-(Trifluoromethyl)pyridin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient incorporation of a polar, electron-deficient pyridine motif with enhanced metabolic stability. The primary alcohol functionality facilitates straightforward derivatization—via esterification, ether formation, or oxidation to the carboxylic acid—while maintaining compatibility with diverse reaction conditions. Its bench-stable nature and clean handling profile support reliable use in multi-step synthesis and high-throughput screening workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: