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Structure of 306761-54-6
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This trifluoromethyl-substituted amine features a sterically hindered tertiary amine core, delivering enhanced stability and solubility in organic media. The electron-withdrawing trifluoromethyl group modulates basicity and imparts resistance to oxidation, enabling reliable use in synthesis under standard conditions.
2-(4-(Trifluoromethyl)phenyl)propan-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine functionalization. Its trifluoromethylated aryl group imparts enhanced metabolic stability and lipophilicity, while the tertiary amine functionality facilitates efficient coupling reactions and salt formation. The molecule exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it well-suited for high-throughput synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: