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CS-W001157 4
Total: USD 88.00

(3-Hydroxyphenyl)boronic acid

  • CAS No. 87199-18-6

  • Cat. No. CS-W002734
  • Purity≥98%
  • MDL No.MFCD01074603

*For research and further manufacturing use only, not for direct human use.

(3-Hydroxyphenyl)boronic acid|CS-W002734

Structure of 87199-18-6

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General Information

  • CAS No. 87199-18-6
  • Cat. No. CS-W002734
  • Purity ≥98%
  • MDL No. MFCD01074603
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BO₃
  • Molecular Weight 137.93
  • Synonym(s) 3-Hydroxybenzeneboronic acid
  • SMILES OB(C1=CC=CC(O)=C1)O

Application

(3-Hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its phenolic functionality offers enhanced solubility and stability compared to unsubstituted arylboronic acids, while maintaining compatibility with common protecting groups. The compound facilitates the synthesis of substituted biaryls and functionalized heterocycles relevant to pharmaceutical and materials chemistry.

Synthesis

  • Route1
    • null|null
      121-43-7
    • null|null
      591-20-8
    • ~59%
    • In-stock
      (3-Hydroxyphenyl)boronic acid|CS-W002734
      87199-18-6

    References

    • Brown, William; Walpole, Christopher; Wei, Zhongyong Patent: US2003/187022 A1, 2003 ;
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 54, p. 4415,4418
  • Route3
    • null|null
      108-43-0
    • ~%
    • In-stock
      (3-Hydroxyphenyl)boronic acid|CS-W002734
      87199-18-6

    References

    • Journal of the American Chemical Society, , vol. 134, # 28 p. 11667 - 11673

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   60.69
  • LogP   -0.928
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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