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CS-W001157 4
Total: USD 88.00

3,5-Dichloropyridazine

  • CAS No. 1837-55-4

  • Cat. No. CS-D0778
  • Purity≥98%
  • MDL No.MFCD10698048

*For research and further manufacturing use only, not for direct human use.

3,5-Dichloropyridazine|CS-D0778

Structure of 1837-55-4

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General Information

  • CAS No. 1837-55-4
  • Cat. No. CS-D0778
  • Purity ≥98%
  • MDL No. MFCD10698048
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂Cl₂N₂
  • Molecular Weight 148.98
  • Synonym(s) 3,5-Dichloropyridazine
  • SMILES ClC1=CC(Cl)=NN=C1

Description

3,5-Dichloropyridazine is a heterocyclic building block featuring two chlorine substituents at electron-deficient positions, enabling facile functionalization via palladium-catalyzed cross-coupling. This bench-stable scaffold integrates readily into bioactive molecules and advanced materials, offering enhanced reactivity and selectivity in synthetic transformations.

Application

3,5-Dichloropyridazine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient functionalization via palladium-catalyzed cross-coupling reactions. Its electron-deficient pyridazine core exhibits excellent stability under standard reaction conditions, while the ortho-chlorine substituents provide high regioselectivity for nucleophilic substitution. This enables straightforward access to diverse substituted heterocycles and complex scaffolds relevant to API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.7834
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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