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Structure of 301836-57-7
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2,3-Dihydrobenzofuran-6-carboxylic acid features a rigid, oxygen-containing heterocyclic core paired with a carboxylic acid handle, enabling direct incorporation into bioactive scaffolds. This bench-stable, moisture-tolerant building block integrates seamlessly into medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
2,3-Dihydrobenzofuran-6-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its bench-stable carboxylic acid group facilitates efficient amide bond formation, esterification, and derivatization, while the fused dihydrofuran core provides structural rigidity and favorable pharmacokinetic properties. Functions effectively in peptide coupling, Suzuki-Miyaura cross-coupling, and late-stage modifications within synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: