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CS-W001157 4
Total: USD 88.00

4-Methyl-1,2,5-oxadiazole-3-carboxylic acid

  • CAS No. 58677-34-2

  • Cat. No. CS-0099433
  • Purity≥96%
  • MDL No.MFCD00461519

*For research and further manufacturing use only, not for direct human use.

4-Methyl-1,2,5-oxadiazole-3-carboxylic acid|CS-0099433

Structure of 58677-34-2

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General Information

  • CAS No. 58677-34-2
  • Cat. No. CS-0099433
  • Purity ≥96%
  • MDL No. MFCD00461519
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄N₂O₃
  • Molecular Weight 128.09
  • Synonym(s) 3-methylfurazan-4-carboxylic acid
  • SMILES O=C(O)C1=NON=C1C

Description

4-Methyl-1,2,5-oxadiazole-3-carboxylic acid is a bench-stable heterocyclic building block featuring a fused oxadiazole ring with a methyl-substituted carbon adjacent to the carboxylic acid. This electron-deficient scaffold integrates readily into bioconjugation and medicinal chemistry applications, offering enhanced metabolic stability and controlled reactivity in synthetic transformations.

Application

4-Methyl-1,2,5-oxadiazole-3-carboxylic acid serves as a stable, bench-ready building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through established coupling and functionalization protocols. Its carboxylic acid group facilitates direct derivatization, while the 1,2,5-oxadiazole core provides enhanced metabolic stability and favorable physicochemical properties in medicinal chemistry applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.22
  • LogP   0.07622
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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