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CS-W001157 4
Total: USD 88.00

Tris(3-chlorophenyl)phosphine

  • CAS No. 29949-85-7

  • Cat. No. CS-W009776
  • Purity≥95%
  • MDL No.MFCD00013632

*For research and further manufacturing use only, not for direct human use.

Tris(3-chlorophenyl)phosphine|CS-W009776

Structure of 29949-85-7

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General Information

  • CAS No. 29949-85-7
  • Cat. No. CS-W009776
  • Purity ≥95%
  • MDL No. MFCD00013632
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₂Cl₃P
  • Molecular Weight 365.62
  • Synonym(s) tris(3-chlorophenyl)phosphane
  • SMILES ClC1=CC(P(C2=CC=CC(Cl)=C2)C3=CC=CC(Cl)=C3)=CC=C1

Description

Tris(3-chlorophenyl)phosphine features three 3-chlorophenyl groups attached to a central phosphorus atom, delivering enhanced electron-withdrawing character and improved stability in catalytic applications. This sterically encumbered ligand exhibits high thermal resilience and moisture tolerance, enabling reliable performance in cross-coupling reactions under standard conditions.

Application

Tris(3-chlorophenyl)phosphine serves as a robust, bench-stable ligand in palladium-catalyzed cross-coupling reactions, offering enhanced functional group tolerance due to its electron-withdrawing chloro substituents. It facilitates efficient coupling of aryl halides and pseudohalides under standard conditions, enabling reliable C–C bond formation in complex molecule synthesis. Its steric profile supports high catalytic activity while maintaining ease of purification and handling.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.405
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   3

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