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CS-W001157 4
Total: USD 88.00

4-BocNH-Bicyclo[2.2.2]octane-COOH

  • CAS No. 863304-76-1

  • Cat. No. CS-W001271
  • Purity≥96%
  • MDL No.MFCD22577789
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-BocNH-Bicyclo[2.2.2]octane-COOH|CS-W001271

Structure of 863304-76-1

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Description

4-((tert-Butoxycarbonyl)amino)bicyclo[2.2.2]octane-1-carboxylic acid features a rigid bicyclic core that imparts conformational stability, enabling precise spatial orientation in synthetic applications. The tert-butoxycarbonyl group provides a protected amine handle for subsequent deprotection and coupling, while the carboxylic acid moiety supports efficient derivatization under standard conditions. This combination facilitates integration into complex molecular architectures with defined stereochemistry.

Application

4-((tert-Butoxycarbonyl)amino)bicyclo[2.2.2]octane-1-carboxylic acid serves as a stable, bench-accessible building block for the synthesis of constrained amino acid derivatives and peptidomimetics. The tert-butoxycarbonyl (Boc) group provides excellent protection for primary amines during multi-step syntheses, while the rigid bicyclic core imparts conformational constraint ideal for probing bioactive conformations in medicinal chemistry. Its compatibility with standard coupling protocols and ease of deprotection under mild acidic conditions facilitates efficient incorporation into complex molecular architectures.

General Information

  • CAS No. 863304-76-1
  • Cat. No. CS-W001271
  • Purity ≥96%
  • MDL No. MFCD22577789
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₃NO₄
  • Molecular Weight 269.34
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC12CCC(C(=O)O)(CC1)CC2

Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.6887
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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