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CS-W001157 4
Total: USD 88.00

Tris(4-bromophenyl)phosphane

  • CAS No. 29949-81-3

  • Cat. No. CS-0157423
  • Molecule weight498.97
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tris(4-bromophenyl)phosphane|CS-0157423

Structure of 29949-81-3

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General Information

  • CAS No. 29949-81-3
  • Cat. No. CS-0157423
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₂Br₃P
  • Molecular Weight 498.97
  • Synonym(s) tris-para-bromophenylphosphane
  • SMILES C1=C(C=CC(=C1)P(C2=CC=C(C=C2)Br)C3=CC=C(C=C3)Br)Br

Description

Tris(4-bromophenyl)phosphane features three 4-bromophenyl groups attached to a central phosphorus atom, delivering high reactivity in cross-coupling processes. The bromine substituents enable direct functionalization while maintaining stability under standard conditions. This bench-stable reagent integrates seamlessly into palladium-catalyzed transformations, offering reliable performance in the synthesis of complex arylated architectures.

Application

Tris(4-bromophenyl)phosphane serves as a versatile phosphine reagent in cross-coupling reactions, enabling efficient Suzuki-Miyaura and Negishi-type transformations. Its brominated aryl groups provide enhanced stability and facilitate further functionalization. The compound exhibits excellent bench stability, mild handling requirements, and tolerates a range of functional groups, making it ideal for iterative synthesis and scale-up applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.7323
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   3

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