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CS-W001157 4
Total: USD 88.00

1,5-Bis(diphenylphosphino)pentane

  • CAS No. 27721-02-4

  • Cat. No. CS-W011601
  • Purity≥95%
  • MDL No.MFCD00003052

*For research and further manufacturing use only, not for direct human use.

1,5-Bis(diphenylphosphino)pentane|CS-W011601

Structure of 27721-02-4

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General Information

  • CAS No. 27721-02-4
  • Cat. No. CS-W011601
  • Purity ≥95%
  • MDL No. MFCD00003052
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₃₀P₂
  • Molecular Weight 440.51
  • Synonym(s) Pentamethylenebis(diphenylphosphine)
  • SMILES C(CCP(C1=CC=CC=C1)C1=CC=CC=C1)CCP(C1=CC=CC=C1)C1=CC=CC=C1

Description

A pyridine derivative used in the preparation of inhibitors of Acyl CoA, cholesterol acyltransferase as well as bone morphogenetic protein (BMP) signaling inhibitors.

Application

1,5-Bis(diphenylphosphino)pentane serves as a versatile bidentate phosphine ligand in transition metal catalysis, enabling efficient cross-coupling and hydrogenation reactions. Its flexible pentylene backbone and robust diphenylphosphino groups provide strong metal coordination, enhanced stability, and compatibility with palladium- and nickel-catalyzed transformations. The ligand’s bench-stable nature and ease of purification make it ideal for reproducible, scalable synthetic workflows.

Synthesis

  • Route1
    • null|null
      628-76-2
    • null|null
      7439-93-2
    • null|null
      603-35-0
    • ~34%
    • In-stock
      1,5-Bis(diphenylphosphino)pentane|CS-W011601
      27721-02-4

    References

    • Shatunov; Korlyukov; Lebedev; Sheludyakov; Kozyrkin; Orlov, V.Yu. Journal of Organometallic Chemistry, 2011 , vol. 696, # 10 p. 2238 - 2251
  • Route2
    • null|null
      111-24-0
    • null|null
      829-85-6
    • ~64%
    • In-stock
      1,5-Bis(diphenylphosphino)pentane|CS-W011601
      27721-02-4

    References

    • Honaker, Matthew T.; Salvatore, Ralph Nicholas Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 2 p. 277 - 283

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   6.4225
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   10

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