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CS-W001157 4
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(R)-4-(tert-Butyl)-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole

  • CAS No. 2757082-56-5

  • Cat. No. CS-0179435
  • Molecule weight255.31
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-4-(tert-Butyl)-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole|CS-0179435

Structure of 2757082-56-5

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General Information

  • CAS No. 2757082-56-5
  • Cat. No. CS-0179435
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₇N₃O
  • Molecular Weight 255.31
  • Synonym(s) None
  • SMILES CC([C@@H]1COC(C2=NC3=NC=CC=C3C=C2)=N1)(C)C

Description

(R)-4-(tert-Butyl)-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole is a sterically encumbered heterocyclic scaffold featuring a chiral oxazole core paired with a fused naphthyridine system. This configuration imparts enhanced metabolic stability and favorable binding geometry for targeted small-molecule applications in medicinal chemistry.

Application

(R)-4-(tert-Butyl)-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds via standard coupling and cyclization protocols. Its stability under ambient conditions, combined with orthogonal functional group tolerance, facilitates straightforward purification and integration into complex molecular architectures relevant to drug discovery programs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   47.37
  • LogP   2.8213
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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